IN SILICO SCREENING OF KNOWN SMALL MOLECULES TO BIND ACE2 SPECIFIC RBD ON SPIKE GLYCOPROTEIN OF SARS-COV-2 FOR REPURPOSING AGAINST COVID-19 [VERSION 1; PEER REVIEW: 2 APPROVED]

Background: Human coronavirus (SARS-CoV-2) is causing a pandemic with significant morbidity and mortality.As no effective novel drugs are available currently, drug repurposing is an alternative intervention strategy.Here we present an in silico drug repurposing study that implements successful concepts of computer-aided drug design (CADD) technolog

In order to better implement the water environmental management policies, water quality evaluation is the basic step, that is to reasonably divide it into specific water quality category according to multiple water quality parameters in a certain water area.Aimed at this problem, an improved Naive Bayes classification method was proposed, which end

The purpose of this study is to explain the development of scientific publications on Islamic banking based on year, country, authors, and fields of science that are focused on mapping topics.This study used a qualitative method to review 696 articles Custom Shaped Wooden Ornament published in Scopus indexed scientific journals and the collection o

The tumor microenvironment (TME) is important in the pathogenesis and prognosis of lymphoma.Previous studies have demonstrated that features of the diffuse large B-cell lymphoma (DLBCL) TME can be associated with prognosis, but questions remain about the mechanisms underlying these TME features, and the interplay between tumor cells and the local T